09.30am, CT - The 2021 Digital Summit will start with a 30-minute networking session to give all delegates the opportunity to get to know the Probiota Community.
From Artificial Intelligence to Microbial Intelligence
Introduction from our Chair of the Digital Summit, Stephen Daniells, Editor-in-Chief, NutraIngredients-USA
Anna Paola Carrieri, PhD,
Research Staff Member,
Anna will present on: Explainable AI reveals changes in microbiome composition linked to phenotypic differences.
The fusion of artificial intelligence with rich microbiome datasets can offer an improved understanding of the microbiome’s role in human health. To gain actionable insights, it is essential to consider both the predictive power and the transparency of the models by providing explanations for the predictions.
IBM presents an explainable artificial intelligence approach that provides accurate predictions of host observable traits with explanations. The explanations offer insights into the complex relationships between microbial communities and phenotypes/traits. IBM’s approach can be applied to predict any condition from a person's microbiome and has the potential to accelerate the development of microbiome-based personalized therapeutics and non-invasive diagnostics.
Panel discussion, our chair Stephen Daniells, will be joined by:
- Giovanna Felis , Associate Professor, University of Verona, Italy
- Rodolphe Barrangou, PhD, T. R. Klaenhammer Distinguished Professor in Probiotics Research, North Carolina State University
- Zachary Abott, CEO & Founder, Zbiotics
- Raja Dhir , Co-Founder & Co-CEO, Seed Health
The panel discussion will be followed by a presentation.
Tom Coenye, PhD
Tom's will present on: Intelligent microbial life: cell-cell communication in the human microbiome
Many human and animal pathogens use quorum sensing (i.e. the exchange of chemical signalling molecules) to ‘talk’ to each other and to coordinate their behavior. Quorum sensing controls various important phenotypes in bacterial pathogens, including virulence and antimicrobial susceptibility, and is involved in mediating (beneficial and pathogenic) interactions with the host. In his presentation Tom will share examples of his work on communication between different players (pathogens, commensals, host cells) in the human body and will illustrate how this can lead to innovative approaches to treatment of various infectious and inflammatory gastrointestinal and respiratory diseases.
- Microorganisms can coordinate their behavior by communicating to each in a process called quorum sensing
- Several important microbial phenotypes are controlled by quorum sensing, making it an attractive target to modulate microbial behavior
- Communication between bacteria as well as communication between bacteria and the host play important roles in regulating important physiological processes
Tom's presentation will be followed by a short Q&A session with Stephen Daniells, PhD
The Q&A session will be followed by a presentation.
Catherina Koning, Head of Education and senior scientist, Winclove
Catherina's will present on: Optimizing metabolic health: A role for probiotics?
Insulin resistance and systemic low-grade inflammation seem to be at the core of metabolic disorders. Recent research has indicated that the gut microbiota plays an important role in managing metabolic health. Disturbance of gut microbiota by a typical western lifestyle leads to changes in serum lipopolysaccharides, short-chain fatty acids, and bile acid, resulting in systemic low-grade inflammation and insulin resistance. Given the role of the microbiota on metabolic disorders, targeted probiotic formulations may be clinically relevant for optimizing metabolic health, influencing insulin resistance and systemic low-grade inflammation associated in early- and late-stage metabolic disorder, specifically T2DM.
Today a record number of patients worldwide suffer from metabolic disorders, including obesity, non-alcoholic fatty liver disease (NAFLD), type 2 diabetes mellitus (T2D). The gut microbiota plays an important role in insulin resistance and low-grade inflammation, which are two core factors implicated in metabolic disease. By lowering insulin resistance and reducing low-grade inflammation, the multispecies probiotic Ecologic® BARRIER helps to optimize metabolic health and manage pre- and early-stage disease progression in diabetes mellitus
– put your questions to our panelists and keynote speakers
Anna Paola Carrieri, PhD
*There will be live chat, Q&A and polling throughout the session
12.00pm, CT - Networking - the opportunity to chat to other delegates, schedule one-on-one meetings, visit our sponsor hubs and view our Scientific Frontiers posters.
2.00pm, CT -
The second session on
Beyond Probiotics: Prebiotics, Synbiotics and Postbiotics,
more details can be found