Bruno graduated from the University of Gent, Belgium. In subsequent postdocs he performed research on lactic acid bacteria. In 1997 he joined the company Yakult as science manager Benelux. Between 2001–2016 he worked as Research Director at the Institut Pasteur in Lille and as as Director of Business Development at the bioinformatics company Applied Maths NV. Since 2016 Bruno is back with Yakult as Science Director Europe. He is member of the Taxonomic Subcommittee for Lactobacillus and Bifidobacterium, President of the Pharmabiotic Research Institute, and board member of ILSI-EU and the LABIP.